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[JN14820]兔抗TXNIP多克隆抗体

价格:0

货号:JN14820

规格: 100ul 200ul 25ul

联系方式:021-54479081

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中文名称:  兔抗TXNIP多克隆抗体

英文名称: Anti-TXNIP rabbit polyclonal antibody

别       名: THIF; VDUP1; HHCPA78; EST01027

相关类别: 一抗

储       存: 冷冻(-20℃)

宿       主: Rabbit

抗       原: TXNIP

反 应种属 : Human, Mouse, Rat

标 记  物: Unconjugate

克隆类型: rabbit polyclonal

技术规格


Background:

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).

Applications:

ELISA, IHC

Name of antibody:

TXNIP

Immunogen:

Synthetic peptide of humanTXNIP

Full name:

thioredoxin interacting protein

Synonyms:

THIF; VDUP1; HHCPA78; EST01027

SwissProt:

Q9H3M7

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

30-150


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